Skip to content
Breathing, swallowing or vision problems: call the emergency services (15 or 112 in France).

Spock brow after Botox: why, how long and what to do

A "Spock brow" is an eyebrow tail that rises into a peak after a botulinum toxin injection. The product labels call it the Mephisto sign. It comes from the outer part of the forehead muscle, which stays active while the centre is relaxed. It is temporary, and a correction can be discussed with your doctor.

A Spock brow, or Mephisto sign, is an eyebrow whose outer part rises into a peak, giving a surprised or stern look. It is one of the most frequently described eyebrow problems after an injection, and one of the easiest to explain. It is harmless and temporary. It most often follows a forehead injection, or forehead and frown line injections during the same session. This page answers the seven questions people ask most often.

Why does the eyebrow rise into a peak?

The forehead muscle is the only muscle that lifts the eyebrows4. It spans the whole width of the forehead, up to above the tail of the eyebrows. When the central part of this muscle is relaxed by the toxin while its outer part stays active, the outer part keeps pulling on the eyebrow tail, which rises on its own: this is the Mephisto sign4.

A review of the complications of botulinum toxin in the upper face describes it as a curving of the eyebrow tail caused by an imbalance between the centre of the frontalis muscle, which has been switched off, and its lateral parts, which remain active4. The same review explains that the eyebrow tail can rise when the muscle is not blocked at the sides while it is blocked in the centre4. Forehead anatomy varies a great deal from one person to another: the distribution of injection points needs to take into account the shape and strength of each muscle5.

The official labels describe this effect. For one type A toxin, the Mephisto sign is uncommon after treatment of frown lines alone, and common after treatment of the forehead combined with frown lines1. With another type A toxin, it is listed as common after treatment of frown lines2. With the short-acting botulinum toxin (serotype E), approved for frown lines only, it was reported in 0.04% of patients, which classifies it as a rare effect3. These figures come from different trials and cannot be used to compare the products.

How soon after the injection does it appear?

A Spock brow appears as the effect of the toxin on the centre of the forehead builds up. With a type A toxin, first effects are usually seen within 2–3 days, with the peak effect at day 30 for frown lines2. With the short-acting toxin, first effects appear from 8 hours and the peak effect is reached around day 73. The eyebrow can therefore rise during the first few days, and its shape may become clearer up to the peak effect.

How long does it last?

As long as the effect of the product injected. With a type A toxin, the effect on frown lines has been shown for up to 4 months1. With the short-acting toxin, the effect usually lasts 2–3 weeks3. This toxin has been approved in the European Union since 15 July 2026 and in Canada since 22 June 20266,7. Duration therefore depends on the toxin used: the page that sets out a comparison of the two families of toxins summarises these profiles, and the page on how long botulinum toxin lasts gives the details product by product.

Is it reversible?

Yes. When the effect of the toxin on the centre of the forehead wears off, the centre regains its strength, the balance with the lateral parts returns and the eyebrow goes back to its usual shape. No lasting effect is described in the sources we consulted.

Is there a treatment?

Yes. The correction described in the literature consists of adding a little toxin into the part of the muscle that remains active, that is, at the side of the forehead, above the eyebrow tail4. The eyebrow comes down once this top-up starts to work. It is often a simple correction, but it is decided after an examination: the doctor checks that the eyebrow is not in fact low on the other side, and doses the top-up so that the eyebrow tail does not drop.

No dose is given here: the units of different toxins are not interchangeable3. If the first injection was done with a short-acting toxin, note that a type A toxin injected less than 30 days afterwards has not been evaluated3, and nor have repeat injections of the short-acting toxin less than 6 weeks apart3. The doctor takes this into account when deciding whether to correct or to wait.

What should you avoid?

Avoid having the eyebrow corrected by a practitioner who does not know about the previous session: they need to know which points were injected, with which product and on what date. Avoid frowning or raising your eyebrows in an exaggerated way to "test" the result in the first few days: the eyebrow is judged at rest and in natural expression. Do not try to "bring the eyebrow down" with massage: no effect is described in the sources we consulted.

When should you see a doctor?

Talk to the doctor who performed the injection as soon as the shape of the eyebrow bothers you, to find out whether a correction would help and when. A Spock brow on its own does not require urgent care. On the other hand, see a doctor promptly if an eyebrow or eyelid droops enough to get in the way of your vision, or if your vision is blurred or double. A photo from the front, at rest and with your eyebrows raised, helps the doctor assess it.

When to seek medical advice quickly

  • Blurred or double vision
  • Difficulty swallowing, speaking or breathing

Breathing, swallowing or vision problems: call the emergency services (15 or 112 in France).

A Spock brow sometimes appears on one side only: in that case, see the page on uneven eyebrows. An over-strong correction can on the contrary make the eyebrow tail drop, a situation described on the page about the eyebrow that droops after an injection. If it is mainly your forehead that no longer moves, the page on the frozen forehead after an injection is for you.

Key points

  • A Spock brow, or Mephisto sign, comes from the outer part of the forehead muscle staying active while the centre is relaxed4.
  • It is described in the labels of type A toxins as well as in that of the short-acting toxin, with varying frequencies1,2,3.
  • It lasts as long as the product’s effect: up to 4 months for a type A toxin, 2–3 weeks for the short-acting toxin1,3.
  • A small top-up at the side of the forehead can correct it, after an examination by the doctor4.

Frequently asked questions

  • Why is it called the Mephisto sign?

    It is the term used in the official labels of botulinum toxins for elevation of the outer part of the eyebrows1,3. The eyebrow takes on a peaked, circumflex shape reminiscent of depictions of Mephistopheles, or of the character Spock in popular culture. Both expressions describe exactly the same effect, which is why you will find both names used for it.

  • Can a Spock brow correct itself?

    Yes, with time. The eyebrow returns to its usual shape when the effect of the toxin on the centre of the forehead wears off and the balance between the different parts of the muscle returns. This takes as long as the effect of the product injected, which means several months for a type A toxin1. If you would rather not wait, a small correction can be discussed with your doctor4.

Sources

  1. 1.SmPC of a type A botulinum toxin approved for aesthetic use in France (BDPM, CIS 68150775) (opens in a new tab) — French public medicines database (BDPM)
  2. 2.SmPC of a type A botulinum toxin approved for aesthetic use in France (BDPM, CIS 61592762) (opens in a new tab) — French public medicines database (BDPM)
  3. 3.Summary of product characteristics of the serotype E botulinum toxin approved in the European Union (EPAR annex I) (opens in a new tab) — European Commission (Union Register of medicinal products)
  4. 4.Borba A. et al., avoiding complications of upper face treatment with botulinum toxin: a practical guide, Aesthetic Plastic Surgery, 2022 (opens in a new tab) — Aesthetic Plastic Surgery
  5. 5.Lorenc Z.P. et al., functional anatomy of the frontalis and glabellar complex for type A botulinum toxin therapy, Aesthetic Plastic Surgery, 2013 (opens in a new tab) — Aesthetic Plastic Surgery
  6. 6.European public assessment report (EPAR) of the serotype E botulinum toxin (opens in a new tab) — European Commission (Union Register of medicinal products)
  7. 7.Canadian product monograph of the serotype E botulinum toxin (authorization date: 2026-06-22) (opens in a new tab) — Health Canada
Book an appointmentSOS after an injection